DOWN
Definition of DOWN
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A negative aspect; a downer.
"I love almost everything about my job. The only down is that I can't take Saturdays off."
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A grudge (on someone).
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An act of swallowing an entire drink at once.
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To knock (someone or something) down; to cause to come down, to fell.
"A single rifle shot downed the mighty beast."
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To lower; to put (something) down.
"The bell rang for lunch, and the workers downed their tools."
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To defeat; to overpower.
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Sad, unhappy, depressed, feeling low.
"Mary seems very down since she split up with her boyfriend."
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(normally in the combination 'down with') Sick or ill.
"He is down with the flu."
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At a lower level than before.
"Prices are down."
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From a higher position to a lower one; downwards.
"The cat jumped down from the table."
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At a lower or further place or position along a set path.
"His place is farther down the road."
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South (as south is at the bottom of typical maps).
"I went down to Miami for a conference."
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From the higher end to the lower of.
"The ball rolled down the hill."
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From nouth to south of.
"We sailed down the eastern seaboard."
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From one end to another of (in any direction); along.
"The bus went down the street."
Source: Wiktionary